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Nanocalorimeter and Raman microscope combination technique to study polymorphic transition processes in pharmacy materials

https://doi.org/10.35164/0554-2901-2024-02-36-38

Abstract

This article describes an experimental setup for combining ultrafast on-chip calorimetry (nanocalorimetry) and Raman spectroscopy (Raman spectroscopy) to study phase transformations in polymer materials. A new method for calibration of a nanocalorimetric sensor under a laser beam of a Raman microscope for in situ measurements at various temperatures is developed.

About the Authors

A. A. Akhkiamova
Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS; Lomonosov Moscow State University; National University of Science and Technology MISiS
Russian Federation

Moscow region, Chernogolovka;

Moscow



A. F. Abukaev
Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS; Lomonosov Moscow State University; National University of Science and Technology MISiS
Russian Federation

Moscow region, Chernogolovka;

Moscow



A. P. Melnikov
Lomonosov Moscow State University
Russian Federation

Moscow



E. V. Komov
Lomonosov Moscow State University
Russian Federation

Moscow



I. I. Rulev
National University of Science and Technology MISiS
Russian Federation

Moscow,



D. A. Ivanov
Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS; Lomonosov Moscow State University; Sirius University of Science and Technology; National University of Science and Technology MISiS
Russian Federation

Moscow region, Chernogolovka;

Moscow;

Sochi



References

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3. Anokhin D.V., Gorbunova M.A., Estrin Y.I., Komratova V.V., Badamshina E.R. The role of fast and slow processes in the formation of structure and properties of thermoplastic polyurethanes // Physical Chemistry Chemical Physics. 2016. V. 18, P. 31769.

4. Hédoux A., Decroix A.-A., Guinet Y., Paccou L., Derollez P., Descamps M.J. Thermodynamic properties of caff eine crystal forms // Physical Chemistry B. 2011. V. 115. P. 5746.

5. Иванов Д.А., Ахкямова А.Ф., Пирязев А.А., Комов Е.В., Бовсуновская П.В. Универсальная платформа для проведения комбинированных in situ измерений теплофизических, спектроскопических и структурных параметров образца // Патент RU 211395 U1. 2022.


Review

For citations:


Akhkiamova A.A., Abukaev A.F., Melnikov A.P., Komov E.V., Rulev I.I., Ivanov D.A. Nanocalorimeter and Raman microscope combination technique to study polymorphic transition processes in pharmacy materials. Plasticheskie massy. 2024;(2):36-38. (In Russ.) https://doi.org/10.35164/0554-2901-2024-02-36-38

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ISSN 0554-2901 (Print)